John E.

Olerud

MD

Biography

Dr. John Olerud is a board certified physician at the Fred Hutchinson Cancer Center. Dr. Olerud has been a member of the UW Department of Dermatology for over 50 years and has contributed to the education and clinical excellence of the Department and University in a variety of capacities including a former Director of the Dermatology Residency Program and Head of the Department from 1988-2014. Dr. Olerud is renowned for his research, with over 100 publications on a variety of skin conditions and treatment modalities as well as his patient care. Over the years, Dr. Olerud has cared for countless patients and has received various honors, notably the Seattle Top Doc designation chosen by patients for over 10 years. UW Derm established The John E. Olerud Resident Teaching Award and the John E. Olerud Professorship for Dermatology in his honor in 2005 and 2007 respectively.

Dr. Olerud has held membership and responsibilities in national professional organizations throughout his career including the American Academy of Dermatology, the American Skin Association and the Association of Professors of Dermatology.

Education & Training

MD, University of Washington School of Medicine, Seattle WA (1971)

Residency in Internal Medicine, University of Washington, Seattle WA (1975)

Residency in Dermatology, University of Washington, Seattle WA (1977)

Honors 

Seattle Metropolitan Top Doctor (2015)

Seattle Top Doc (Seattle Met Magazine) (2020)

Research Interests

• Abnormal wound healing in patients with diabetes mellitus
• Cutaneous T-cell lymphoma; and biomaterials/skin interface

Clinical Interests 

• Cutaneous lymphoma
• Skin manifestations of diabetes and internal diseases
• Leg ulcers and connective tissue diseases

Publications

Selected Publications

Olerud JE. Models for Wound Healing and Healing into Percutaneous Devices. J Biomat Sci, Polymer Edn Vol. 19, No. 8, pp. 1007-20, 2008. PMID 18644227

Fukano Y, Usui ML, Underwood RA, Isenhath S, Marshall AJ, Hauch KD, Ratner BD, Olerud JE, Fleckman P. Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice. J Biomed Mater Res A. Sep 15;94(4):1172-86, 2010. PMID: 20694984

Zhao G, Hochwalt PC, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE. Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds, Wound Repair Regen. 2010 18(5):467-77, 2010. PMID: 20731798

Kalus AA, Chien AC, Olerud JE. Chapter 152: Diabetes mellitus and other endocrine diseases, in Fitzpatrick?s Dermatology in General Medicine 8th edition, in press. Eds. Wolff, Goldsmith, Katz, et al, McGraw-Hill, In Press, 2010.

Secor PR, James GA, Fleckman PH, Olerud JE, McInnerney K, Stewart PS.  Staphylococcus aureus biofilm and planktonic cultures differentially impact gene Expression, MAPK phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol. Jun;11:143, 2011.  PMID: 21693040, PMCID: PMC3146417

Fleckman P, Usui ML, Zhao GA, Underwood RA, Maginness M, Marshall A, Glaister C, Ratner R, Olerud JE.  Cutaneous and inflammatory response to long-term percutaneous implants of sphere-templated porous/solid poly(HEMA) and silicone in Mice.  J Biomed Mat Res A. Feb 23, 2012. [Epub ahead of print].  PMID: 22359383

Kirker KR, James GA, Fleckman PH, Olerud JE, Stewart PS.  Differential Effects of Planktonic and Biofilm MRSA on Human Fibroblasts.  Wound Repair Regen. Mar-Apr;20(2):253-61, 2012. Epub Feb 14, 2012.  PMID: 22332802, PMCID: PMC3292663

Secor PR, Jennings LK, James GA, Kirker KR, Pulcini ED, McInnerney K, Gerlach R, Livinghouse, Hilmer JK, Bothner B, Fleckman P, Olerud JE, Stewart PS.  Phevalin (aureusimine B) Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression. PLoS One. 7(7):e40973, 2012.  PMID: 22808288, PMCID: PMC 3396627

Zhao G, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE.  Time course study of delayed wound healing in a biofilm-challenged diabetic mouse model. Wound Repair Regen. 20(3):342-52, 2012.  PMID: 22564229, PMCID: PMC 3349451

Usui ML, Underwood RA, Fleckman P, Olerud JE.  Parakeratotic corneocytes play a unique role in human skin wound healing. J Invest Dermatol. 2013 Mar;133(3):856-8. doi: 10.1038/jid.2012.352. Epub Sep 27, 2012. PMID: 23014344 PMCID: PMC3532577

Zhao G, Chamberlain MC, Khot SP, Shustov A, Olerud JE, Shinohara MM.  Central Nervous System Involvement in Cutaneous T-cell Lymphoma: 2 Illustrative Cases and a Review of Current Literature. Clin Lymphoma Myeloma Leuk. Oct 1, 2013. pii: S2152-2650(13)00437-0. doi: 10.1016/j.clml.2013.09.016. PMID: 24262331

Choi W-T, Stetsenko GY, Zhang J, Olerud JE, Argenyi ZB, George E.  Cutaneous angiosarcoma clinically presenting as progressive solid facial edema in a 43-your-old male. Dermatol Online J. 19(11):20409, Nov 15, 2013. PMID: 24314784

Zhao G, Usui ML, Lippman S, James GA, Stewart PS, Fleckman P, Olerud JE. Biofilms and Inflammation in Chronic Wounds, 2013.